By Harry Salem,Sidney A. Katz
In over forty chapters, the booklet addresses 7 subject matters, starting with the validation and regulatory recognition of choices within the US, the united kingdom, and Western Europe. Then the publication covers tools in response to the mechanisms of eye inflammation on the ocular floor, dermal toxicity trying out, and assessing neurotoxicity. it's also a case learn within the use of choices to figure out the mechanism of sulfur mustard motion and discusses the function of transgenics and toxicokinetics within the improvement of different toxicity exams. eventually the e-book offers contemporary concepts in choices, together with using archival info, and in silico techniques.
Focusing at the technology and never the politics, substitute Toxicological equipment concisely discusses the applying of state of the art equipment and explores state-of-the-art learn concerning constructing and validating choices to animal checking out. This e-book will profit toxicologists, beauty chemists, pharmacologists, experimental biologists, dermatologists, ophthalmologists, and regulatory officials of their quest for employing the 3Rs to using animals in toxicological checking out of drug applicants, chemical substances, and cosmetics.
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